Ceftaroline-
a new generation of cephalosporin
Bactericidal
Block PBP
Addictive to
other antibiotic, least interaction
Professor
Lipman
CANVAS
study showed effective against MRSA complicated soft tissue infection compared to
vancomycin and aztreonem. Study showed
non inferiority to Vancomycin and aztreonem
Treatment
5-14 days
FOCUS I and
II – study showed effective towards CAP. No clinical data regarding MRSA CAP.
New
combination produce –ceftaroline + avibactem –enhanced gram –ve cover.
