Sunday, September 04, 2011

Causes of thrombocytopenia

Medical always related with your normal life even for causes for thrombocytopenia.
It is just like economic-supply and demand
In thrombocytopenia- if destruction excess or reduced production

Impaied production-
1) drugs=eg cytotoxic
2) virus infection-dengue, HIV
3) infection-leptospirosis
4)megaloblastic
5)MDS
6)leukemia,Myelofibrosis, aplastic anemia
7)solid tumour
summary-drug, infection , blood dyscrasia-MDS, leukemia and solid tumour infiltration to marrow

excessive dest
Immune mediated
ITP
drug induced-penicillins, Grp IIB-IIIa inhibitors
secondary immune-SLE, CLL, heparin)
post tranfusion purpura
DIVC
TTP

sequestration
splenomegaly
diluional
massive tranfusion

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